Ensembl is a genome browser for vertebrate genomes that supports research in comparative genomics, evolution, sequence variation and transcriptional regulation. Ensembl annotate genes, computes multiple alignments, predicts regulatory function and collects disease data. Ensembl tools include BLAST, BLAT, BioMart and the Variant Effect Predictor (VEP) for all supported species.

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• Update to GENCODE 34 (human) and GENCODE M25 (mouse)
• Update of gnomAD genomic allele frequencies to version 3
• New genomes: 3 mammals, 7 fish, 6 birds, 4 reptiles
• Updated genomes: Platypus and Northern Pike
• New interface for configuration of multidimensional track hubs

More release news on our blog

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• 24 Jul 2025: Cool stuff the Ensembl VEP can do: summarise your analysis
• 14 Jul 2025: Job: Genome Annotation Project Leader
• 26 Jun 2025: Cool stuff the Ensembl VEP can do: analysis with RefSeq transcripts